Gene description for TSG101
Gene name	tumor susceptibility 101
Gene symbol	TSG101
Other names/aliases	TSG10 VPS23
Species	Homo sapiens
Experiment description of studies that identified TSG101 in Liver cancer cells
1 Experiment ID 1551 Identified molecule protein Extracellular vesicle type Extracellular vesicles MISEV Large EVs Identification method Western blotting PubMed ID 32082513    Organism Homo sapiens Experiment description Hepatitis A virus structural protein pX interacts with ALIX and promotes the secretion of virions and foreign proteins through exosome-like vesicles Authors Jiang W, Ma P, Deng L, Liu Z, Wang X, Liu X, Long G. Journal name J Extracell Vesicles Publication year 2020 Sample Liver cancer cells Sample name Huh-7 - 10K pellet Isolation/purification methods Differential centrifugation Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Western blotting EV-TRACK -
2 Experiment ID 1552 Identified molecule protein Extracellular vesicle type Extracellular vesicles MISEV Small EVs Identification method Western blotting PubMed ID 32082513    Organism Homo sapiens Experiment description Hepatitis A virus structural protein pX interacts with ALIX and promotes the secretion of virions and foreign proteins through exosome-like vesicles Authors Jiang W, Ma P, Deng L, Liu Z, Wang X, Liu X, Long G. Journal name J Extracell Vesicles Publication year 2020 Sample Liver cancer cells Sample name Huh-7 - 100K pellet Isolation/purification methods Differential centrifugation Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Western blotting EV-TRACK -
3 Experiment ID 1553 Identified molecule protein Extracellular vesicle type Extracellular vesicles MISEV Large EVs Identification method Western blotting PubMed ID 32082513    Organism Homo sapiens Experiment description Hepatitis A virus structural protein pX interacts with ALIX and promotes the secretion of virions and foreign proteins through exosome-like vesicles Authors Jiang W, Ma P, Deng L, Liu Z, Wang X, Liu X, Long G. Journal name J Extracell Vesicles Publication year 2020 Sample Liver cancer cells Sample name Huh-7 - 10K pellet Isolation/purification methods Differential centrifugation Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Western blotting EV-TRACK -
4 Experiment ID 1554 Identified molecule protein Extracellular vesicle type Extracellular vesicles MISEV Small EVs Identification method Western blotting PubMed ID 32082513    Organism Homo sapiens Experiment description Hepatitis A virus structural protein pX interacts with ALIX and promotes the secretion of virions and foreign proteins through exosome-like vesicles Authors Jiang W, Ma P, Deng L, Liu Z, Wang X, Liu X, Long G. Journal name J Extracell Vesicles Publication year 2020 Sample Liver cancer cells Sample name Huh-7 - 100K pellet Isolation/purification methods Differential centrifugation Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Western blotting EV-TRACK -
5 Experiment ID 1565 Identified molecule protein Extracellular vesicle type Extracellular vesicles MISEV Small EVs Identification method Western blotting PubMed ID 32082513    Organism Homo sapiens Experiment description Hepatitis A virus structural protein pX interacts with ALIX and promotes the secretion of virions and foreign proteins through exosome-like vesicles Authors Jiang W, Ma P, Deng L, Liu Z, Wang X, Liu X, Long G. Journal name J Extracell Vesicles Publication year 2020 Sample Liver cancer cells Sample name Huh-7 Isolation/purification methods Differential centrifugation Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Western blotting EV-TRACK -
6 Experiment ID 2437 Identified molecule Protein Extracellular vesicle type Exosomes MISEV Small EVs Identification method Western blotting PubMed ID 29335551    Organism Homo sapiens Experiment description Tumor-derived exosomal miR-1247-3p induces cancer-associated fibroblast activation to foster lung metastasis of liver cancer Authors Fang T, Lv H, Lv G, Li T, Wang C, Han Q, Yu L, Su B, Guo L, Huang S, Cao D, Tang L, Tang S, Wu M, Yang W, Wang H. Journal name Nat Commun Publication year 2018 Sample Liver cancer cells Sample name CSQT-2 Isolation/purification methods Filtration Differential centrifugation Ultracentrifugation Flotation density - Molecules identified in the study Protein miRNA Methods used in the study Western blotting Microarray qRT-PCR EV-TRACK -
7 Experiment ID 2438 Identified molecule Protein Extracellular vesicle type Exosomes MISEV Small EVs Identification method Western blotting PubMed ID 29335551    Organism Homo sapiens Experiment description Tumor-derived exosomal miR-1247-3p induces cancer-associated fibroblast activation to foster lung metastasis of liver cancer Authors Fang T, Lv H, Lv G, Li T, Wang C, Han Q, Yu L, Su B, Guo L, Huang S, Cao D, Tang L, Tang S, Wu M, Yang W, Wang H. Journal name Nat Commun Publication year 2018 Sample Liver cancer cells Sample name HCC-LM3 Isolation/purification methods Filtration Differential centrifugation Ultracentrifugation Flotation density - Molecules identified in the study Protein miRNA Methods used in the study Western blotting Microarray qRT-PCR EV-TRACK -
8 Experiment ID 2439 Identified molecule Protein Extracellular vesicle type Exosomes MISEV Small EVs Identification method Western blotting PubMed ID 29335551    Organism Homo sapiens Experiment description Tumor-derived exosomal miR-1247-3p induces cancer-associated fibroblast activation to foster lung metastasis of liver cancer Authors Fang T, Lv H, Lv G, Li T, Wang C, Han Q, Yu L, Su B, Guo L, Huang S, Cao D, Tang L, Tang S, Wu M, Yang W, Wang H. Journal name Nat Commun Publication year 2018 Sample Liver cancer cells Sample name HepG2 Isolation/purification methods Filtration Differential centrifugation Ultracentrifugation Flotation density - Molecules identified in the study Protein miRNA Methods used in the study Western blotting Microarray qRT-PCR EV-TRACK -
9 Experiment ID 2440 Identified molecule Protein Extracellular vesicle type Exosomes MISEV Small EVs Identification method Western blotting PubMed ID 29335551    Organism Homo sapiens Experiment description Tumor-derived exosomal miR-1247-3p induces cancer-associated fibroblast activation to foster lung metastasis of liver cancer Authors Fang T, Lv H, Lv G, Li T, Wang C, Han Q, Yu L, Su B, Guo L, Huang S, Cao D, Tang L, Tang S, Wu M, Yang W, Wang H. Journal name Nat Commun Publication year 2018 Sample Liver cancer cells Sample name MHCC-97L Isolation/purification methods Filtration Differential centrifugation Ultracentrifugation Flotation density - Molecules identified in the study Protein miRNA Methods used in the study Western blotting Microarray qRT-PCR EV-TRACK -
10 Experiment ID 2476 Identified molecule protein Extracellular vesicle type Extracellular vesicles MISEV Small EVs Identification method Western blotting PubMed ID 34401050    Organism Homo sapiens Experiment description TPI1-reduced extracellular vesicles mediated by Rab20 downregulation promotes aerobic glycolysis to drive hepatocarcinogenesis Authors Liu BHM, Tey SK, Mao X, Ma APY, Yeung CLS, Wong SWK, Ng TH, Xu Y, Yao Y, Fung EYM, Tan KV, Khong PL, Ho DW, Ng IO, Tang AHN, Cai SH, Yun JP, Yam JWP. Journal name J Extracell Vesicles Publication year 2021 Sample Liver cancer cells Sample name MHCC97L Isolation/purification methods Differential centrifugation Filtration Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Western blotting Immuno-EM Mass spectrometry EV-TRACK -
11 Experiment ID 2477 Identified molecule protein Extracellular vesicle type Extracellular vesicles MISEV Small EVs Identification method Western blotting PubMed ID 34401050    Organism Homo sapiens Experiment description TPI1-reduced extracellular vesicles mediated by Rab20 downregulation promotes aerobic glycolysis to drive hepatocarcinogenesis Authors Liu BHM, Tey SK, Mao X, Ma APY, Yeung CLS, Wong SWK, Ng TH, Xu Y, Yao Y, Fung EYM, Tan KV, Khong PL, Ho DW, Ng IO, Tang AHN, Cai SH, Yun JP, Yam JWP. Journal name J Extracell Vesicles Publication year 2021 Sample Liver cancer cells Sample name MHCC97L Isolation/purification methods Differential centrifugation Filtration Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Western blotting Immuno-EM Mass spectrometry EV-TRACK -
12 Experiment ID 2481 Identified molecule protein Extracellular vesicle type Extracellular vesicles MISEV Small EVs Identification method Western blotting PubMed ID 34401050    Organism Homo sapiens Experiment description TPI1-reduced extracellular vesicles mediated by Rab20 downregulation promotes aerobic glycolysis to drive hepatocarcinogenesis Authors Liu BHM, Tey SK, Mao X, Ma APY, Yeung CLS, Wong SWK, Ng TH, Xu Y, Yao Y, Fung EYM, Tan KV, Khong PL, Ho DW, Ng IO, Tang AHN, Cai SH, Yun JP, Yam JWP. Journal name J Extracell Vesicles Publication year 2021 Sample Liver cancer cells Sample name PLC/PRF/5 Isolation/purification methods Differential centrifugation Filtration Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Western blotting Immuno-EM EV-TRACK -
13 Experiment ID 2482 Identified molecule protein Extracellular vesicle type Extracellular vesicles MISEV Small EVs Identification method Western blotting PubMed ID 34401050    Organism Homo sapiens Experiment description TPI1-reduced extracellular vesicles mediated by Rab20 downregulation promotes aerobic glycolysis to drive hepatocarcinogenesis Authors Liu BHM, Tey SK, Mao X, Ma APY, Yeung CLS, Wong SWK, Ng TH, Xu Y, Yao Y, Fung EYM, Tan KV, Khong PL, Ho DW, Ng IO, Tang AHN, Cai SH, Yun JP, Yam JWP. Journal name J Extracell Vesicles Publication year 2021 Sample Liver cancer cells Sample name PLC/PRF/5 - clone 1 Isolation/purification methods Differential centrifugation Filtration Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Western blotting Immuno-EM EV-TRACK -
14 Experiment ID 2483 Identified molecule protein Extracellular vesicle type Extracellular vesicles MISEV Small EVs Identification method Western blotting PubMed ID 34401050    Organism Homo sapiens Experiment description TPI1-reduced extracellular vesicles mediated by Rab20 downregulation promotes aerobic glycolysis to drive hepatocarcinogenesis Authors Liu BHM, Tey SK, Mao X, Ma APY, Yeung CLS, Wong SWK, Ng TH, Xu Y, Yao Y, Fung EYM, Tan KV, Khong PL, Ho DW, Ng IO, Tang AHN, Cai SH, Yun JP, Yam JWP. Journal name J Extracell Vesicles Publication year 2021 Sample Liver cancer cells Sample name PLC/PRF/5 - clone 2 Isolation/purification methods Differential centrifugation Filtration Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Western blotting Immuno-EM EV-TRACK -
15 Experiment ID 2484 Identified molecule protein Extracellular vesicle type Extracellular vesicles MISEV Small EVs Identification method Western blotting PubMed ID 34401050    Organism Homo sapiens Experiment description TPI1-reduced extracellular vesicles mediated by Rab20 downregulation promotes aerobic glycolysis to drive hepatocarcinogenesis Authors Liu BHM, Tey SK, Mao X, Ma APY, Yeung CLS, Wong SWK, Ng TH, Xu Y, Yao Y, Fung EYM, Tan KV, Khong PL, Ho DW, Ng IO, Tang AHN, Cai SH, Yun JP, Yam JWP. Journal name J Extracell Vesicles Publication year 2021 Sample Liver cancer cells Sample name MHCC97L Isolation/purification methods Differential centrifugation Filtration Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Western blotting Immuno-EM EV-TRACK -
16 Experiment ID 2485 Identified molecule protein Extracellular vesicle type Extracellular vesicles MISEV Small EVs Identification method Western blotting PubMed ID 34401050    Organism Homo sapiens Experiment description TPI1-reduced extracellular vesicles mediated by Rab20 downregulation promotes aerobic glycolysis to drive hepatocarcinogenesis Authors Liu BHM, Tey SK, Mao X, Ma APY, Yeung CLS, Wong SWK, Ng TH, Xu Y, Yao Y, Fung EYM, Tan KV, Khong PL, Ho DW, Ng IO, Tang AHN, Cai SH, Yun JP, Yam JWP. Journal name J Extracell Vesicles Publication year 2021 Sample Liver cancer cells Sample name MHCC97L Isolation/purification methods Differential centrifugation Filtration Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Western blotting Immuno-EM EV-TRACK -
17 Experiment ID 3088 Identified molecule protein Extracellular vesicle type Extracellular vesicles MISEV Small EVs Identification method Western blotting PubMed ID 36631249    Organism Homo sapiens Experiment description S100A10 promotes HCC development and progression via transfer in extracellular vesicles and regulating their protein cargos Authors Wang X, Huang H, Sze KM, Wang J, Tian L, Lu J, Tsui YM, Ma HT, Lee E, Chen A, Lee J, Wang Y, Yam JWP, Cheung TT, Guan X, Ng IO. Journal name Gut Publication year 2023 Sample Liver cancer cells Sample name PLC Isolation/purification methods Differential centrifugation Filtration Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Western blotting EV-TRACK -
18 Experiment ID 3089 Identified molecule protein Extracellular vesicle type Extracellular vesicles MISEV Small EVs Identification method Western blotting PubMed ID 36631249    Organism Homo sapiens Experiment description S100A10 promotes HCC development and progression via transfer in extracellular vesicles and regulating their protein cargos Authors Wang X, Huang H, Sze KM, Wang J, Tian L, Lu J, Tsui YM, Ma HT, Lee E, Chen A, Lee J, Wang Y, Yam JWP, Cheung TT, Guan X, Ng IO. Journal name Gut Publication year 2023 Sample Liver cancer cells Sample name PLC Isolation/purification methods Differential centrifugation Filtration Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Western blotting EV-TRACK -
19 Experiment ID 3090 Identified molecule protein Extracellular vesicle type Extracellular vesicles MISEV Small EVs Identification method Western blotting PubMed ID 36631249    Organism Homo sapiens Experiment description S100A10 promotes HCC development and progression via transfer in extracellular vesicles and regulating their protein cargos Authors Wang X, Huang H, Sze KM, Wang J, Tian L, Lu J, Tsui YM, Ma HT, Lee E, Chen A, Lee J, Wang Y, Yam JWP, Cheung TT, Guan X, Ng IO. Journal name Gut Publication year 2023 Sample Liver cancer cells Sample name 97L Isolation/purification methods Differential centrifugation Filtration Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Western blotting EV-TRACK -
20 Experiment ID 3091 Identified molecule protein Extracellular vesicle type Extracellular vesicles MISEV Small EVs Identification method Western blotting PubMed ID 36631249    Organism Homo sapiens Experiment description S100A10 promotes HCC development and progression via transfer in extracellular vesicles and regulating their protein cargos Authors Wang X, Huang H, Sze KM, Wang J, Tian L, Lu J, Tsui YM, Ma HT, Lee E, Chen A, Lee J, Wang Y, Yam JWP, Cheung TT, Guan X, Ng IO. Journal name Gut Publication year 2023 Sample Liver cancer cells Sample name 97L Isolation/purification methods Differential centrifugation Filtration Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Western blotting EV-TRACK -
21 Experiment ID 3092 Identified molecule protein Extracellular vesicle type Extracellular vesicles MISEV Small EVs Identification method Western blotting PubMed ID 36631249    Organism Homo sapiens Experiment description S100A10 promotes HCC development and progression via transfer in extracellular vesicles and regulating their protein cargos Authors Wang X, Huang H, Sze KM, Wang J, Tian L, Lu J, Tsui YM, Ma HT, Lee E, Chen A, Lee J, Wang Y, Yam JWP, Cheung TT, Guan X, Ng IO. Journal name Gut Publication year 2023 Sample Liver cancer cells Sample name MIHA Isolation/purification methods Differential centrifugation Filtration Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Western blotting EV-TRACK -
22 Experiment ID 3093 Identified molecule protein Extracellular vesicle type Extracellular vesicles MISEV Small EVs Identification method Western blotting PubMed ID 36631249    Organism Homo sapiens Experiment description S100A10 promotes HCC development and progression via transfer in extracellular vesicles and regulating their protein cargos Authors Wang X, Huang H, Sze KM, Wang J, Tian L, Lu J, Tsui YM, Ma HT, Lee E, Chen A, Lee J, Wang Y, Yam JWP, Cheung TT, Guan X, Ng IO. Journal name Gut Publication year 2023 Sample Liver cancer cells Sample name MIHA Isolation/purification methods Differential centrifugation Filtration Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Western blotting EV-TRACK -
23 Experiment ID 3094 Identified molecule protein Extracellular vesicle type Extracellular vesicles MISEV Small EVs Identification method Western blotting PubMed ID 36631249    Organism Homo sapiens Experiment description S100A10 promotes HCC development and progression via transfer in extracellular vesicles and regulating their protein cargos Authors Wang X, Huang H, Sze KM, Wang J, Tian L, Lu J, Tsui YM, Ma HT, Lee E, Chen A, Lee J, Wang Y, Yam JWP, Cheung TT, Guan X, Ng IO. Journal name Gut Publication year 2023 Sample Liver cancer cells Sample name 97H Isolation/purification methods Differential centrifugation Filtration Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Western blotting EV-TRACK -
24 Experiment ID 3095 Identified molecule protein Extracellular vesicle type Extracellular vesicles MISEV Small EVs Identification method Western blotting PubMed ID 36631249    Organism Homo sapiens Experiment description S100A10 promotes HCC development and progression via transfer in extracellular vesicles and regulating their protein cargos Authors Wang X, Huang H, Sze KM, Wang J, Tian L, Lu J, Tsui YM, Ma HT, Lee E, Chen A, Lee J, Wang Y, Yam JWP, Cheung TT, Guan X, Ng IO. Journal name Gut Publication year 2023 Sample Liver cancer cells Sample name 97H Isolation/purification methods Differential centrifugation Filtration Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Western blotting EV-TRACK -
25 Experiment ID 3098 Identified molecule protein Extracellular vesicle type Extracellular vesicles MISEV Small EVs Identification method Western blotting PubMed ID 36631249    Organism Homo sapiens Experiment description S100A10 promotes HCC development and progression via transfer in extracellular vesicles and regulating their protein cargos Authors Wang X, Huang H, Sze KM, Wang J, Tian L, Lu J, Tsui YM, Ma HT, Lee E, Chen A, Lee J, Wang Y, Yam JWP, Cheung TT, Guan X, Ng IO. Journal name Gut Publication year 2023 Sample Liver cancer cells Sample name 97H Isolation/purification methods Differential centrifugation Filtration Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Western blotting EV-TRACK -
26 Experiment ID 3099 Identified molecule protein Extracellular vesicle type Extracellular vesicles MISEV Small EVs Identification method Western blotting PubMed ID 36631249    Organism Homo sapiens Experiment description S100A10 promotes HCC development and progression via transfer in extracellular vesicles and regulating their protein cargos Authors Wang X, Huang H, Sze KM, Wang J, Tian L, Lu J, Tsui YM, Ma HT, Lee E, Chen A, Lee J, Wang Y, Yam JWP, Cheung TT, Guan X, Ng IO. Journal name Gut Publication year 2023 Sample Liver cancer cells Sample name 97H Isolation/purification methods Differential centrifugation Filtration Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Western blotting EV-TRACK -